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Gum Disease and Alzheimer’s: The Hidden Connection

If you’ve ever noticed bleeding gums when brushing, persistent bad breath, or gum soreness, you may think it’s just a minor dental issue. In reality, these are early signs of gum disease, also called periodontal disease, a chronic infection that not only damages your oral health but also has far-reaching effects on your overall well-being. Left untreated, gum disease progresses from gingivitis to periodontitis, resulting in gum recession, loose teeth, and ultimately, tooth loss.

What’s even more concerning is the growing body of research linking gum disease to Alzheimer’s disease. Multiple studies have detected Porphyromonas gingivalis, a key bacterium in gum disease, in the brains of individuals with Alzheimer’s. This suggests that oral infections may contribute to the formation of amyloid plaques and neuroinflammation, both key hallmarks of Alzheimer’s disease. At MR Dental Aesthetics in Beverly Hills, Dr. Mahnaz Rashti offers cutting-edge treatments to help you reverse gum disease and preserve cognitive health.

What is gum disease?

Gum disease is a progressive infection of the tissues that support your teeth. It begins with gingivitis, where plaque buildup irritates the gums, causing them to become red, swollen, and prone to bleeding. Without timely treatment, it advances to periodontitis, where the infection spreads deeper, damaging bone and connective tissue. This chronic inflammation not only leads to tooth loss but also creates a gateway for bacteria to travel beyond the mouth.

Common signs & symptoms of gum disease:

  • Bleeding gums when brushing or flossing
  • Red, swollen, or tender gums
  • Persistent bad breath or bad taste
  • Receding gums or teeth that appear longer
  • Loose or shifting teeth
  • Painful chewing

How gum disease can lead to Alzheimer’s disease

Recent studies suggest that people with advanced periodontal disease may have nearly double the risk of developing Alzheimer’s within a decade. Gum disease triggers systemic inflammation, allowing bacteria and their toxins to travel through your bloodstream. Once these pathogens penetrate the blood-brain barrier, they can accelerate cognitive decline. Below, we explore the various ways that gum disease can increase the risk of Alzheimer’s disease.

Bacterial invasion of the brain

The bacterium Porphyromonas gingivalis produces toxic enzymes called gingipains. These have been found in the brains of Alzheimer’s patients and are believed to contribute to amyloid-beta plaque buildup, which disrupts communication between brain cells. By addressing gum disease early, you may reduce the chance of these harmful bacteria reaching your brain.

Systemic inflammation and immune response

Chronic gum infections set off a continuous immune response in your body. Over time, this state of low-grade systemic inflammation can lead to neuroinflammation, which in turn damages brain tissue. Elevated levels of inflammatory markers such as TNF-α and IL-1β have been detected in both gum disease and Alzheimer’s, which shows that oral and brain health are closely linked.

woman experiencing gum disease symptoms in Beverly Hills

Impact on vascular health

Gum disease can worsen vascular problems by promoting arterial inflammation and poor circulation. Because vascular health is a critical factor in Alzheimer’s disease, compromised blood flow to the brain can accelerate memory loss and cognitive impairment. Keeping your gums healthy plays a direct role in protecting your cardiovascular and neurological systems.

Microglial activation and nerve cell damage

Microglia are immune cells in the brain responsible for cleaning up damaged tissue. When exposed to periodontal pathogens, microglia become overactive and may release inflammatory chemicals that harm neurons instead of protecting them. This misguided response accelerates neurodegeneration and worsens Alzheimer’s symptoms over time.

Tips to prevent and manage gum disease:

  • Brush teeth twice daily with fluoride toothpaste
  • Floss or use interdental brushes every day
  • Schedule professional dental cleanings every 6 months
  • Reduce high-sugar and high-carbohydrate foods
  • Avoid tobacco in all forms
  • Limit alcohol intake
  • Manage chronic conditions such as diabetes
  • Talk to your dentist about dry mouth linked to medications
  • Stay consistent with regular dental checkups, even with dentures or missing teeth

Reverse the effects of gum disease with Dr. Rashti

At MR Dental Aesthetics, Dr. Rashti takes a comprehensive, health-first approach to treating gum disease and restoring your oral health. Using advanced diagnostic tools and state-of-the-art treatments, she can halt infection, reduce inflammation, and rebuild damaged gum and bone tissue. Her care plans may include deep cleanings, laser therapy, or regenerative techniques to strengthen your foundation for lasting oral health. By treating gum disease early, Dr. Rashti helps you protect your smile and potentially safeguard your brain health.

Your oral health is deeply connected to your overall well-being, and your brain is no exception. Gum disease may seem like a localized condition, but its effects extend far beyond your smile, potentially influencing the development and progression of Alzheimer’s disease. By staying proactive with preventive care and professional dental treatments, you can protect both your oral and cognitive health. Schedule a consultation with Dr. Rashti in Beverly Hills to protect your oral health and, in turn, preserve your memory and cognitive health down the line.

Contact Us 310-623-3330